MEDIDERMA® AZELAC® RU

Manufacturing Information for Azelac RU 60ml

Azelac RU is produced by Mediderma, a distinguished Spanish company known for its expertise in dermatology and skincare.
An extensive range of Mediderma products also includes:

• Azelac M 60ml: An advanced depigmenting solution for more resistant pigmentation issues.
• Azelac Peel Exfoliating Gel 100ml: A gentle yet effective exfoliant that removes dead skin cells and promotes skin renewal.

• C-Defence MD C+Skin Concentrate Serum 30ml: A vitamin C serum that combats oxidative stress and enhances luminosity.
• Ferulac Valencia Peel 50ml: Combines antioxidants with ferulic acid for anti-ageing and brightening benefits.

Expected Benefits and Results of the Treatment

Azelac RU 60ml delivers targeted solutions for pigmentation issues while enhancing skin health. Key benefits include:

• Pigmentation correction: Reduces dark spots, melasma, and uneven skin tone.
• Brightening effect: Improves skin radiance and reduces dullness for a luminous glow.
• Smoother texture: Refines rough patches and minimises the appearance of pores.
• Anti-ageing properties: Reduces fine lines, promotes collagen production, and combats oxidative stress.
• Long-lasting results: Maintains clarity and brightness with cumulative benefits over time.
• Safe for sensitive skin: Gentle yet effective formula suitable for various skin types.

Azelac RU 60ml Key Ingredients

The effectiveness of Azelac RU 60ml lies in its active components, which work synergistically for targeted pigmentation correction:

• 20% Azelaic acid: Reduces melanin production and soothes inflammation.
• 10% Mandelic acid: Gently exfoliates while improving uneven tones.
• 5% Phytic acid: A natural antioxidant that brightens and reduces pigmentation.
• 5% 4n-butyl resorcinol: Targets dark spots and evens out skin tone.
• 2% Ferulic acid: Provides antioxidant defence and stabilizes the formula.

Included Items or Accessories

Azelac RU 60ml comes with all the essentials needed for professional use, ensuring easy and effective application. Inside the package, you will find:

• A 60ml bottle of Azelac RU: The primary product formulated for treating hyperpigmentation and uneven skin tone.
• Detailed instruction leaflet: Comprehensive guidelines for safe and effective use of the product.

Application Method for Azelac RU 60ml

To achieve optimal results and ensure safety, follow these steps for applying Azelac RU 60ml in clinical settings:

Pre-procedure

• Evaluate patient’s skin condition: Assess the patient’s skin type and concerns to ensure suitability for the peel.
• Conduct a patch test: Apply a small amount of the product to a discreet area to test for any adverse reactions.
• Prepare the skin: Cleanse the treatment area thoroughly to remove dirt, oil, and makeup.
• Dry the skin: Ensure the skin is completely dry before applying the peel to avoid uneven absorption.

During procedure

• Dispense the product: Pour a small amount of Azelac RU onto a sterile applicator or gauze pad.
• Apply evenly: Spread a thin, uniform layer across the treatment area, avoiding sensitive regions such as the eyes and mouth.
• Monitor the skin: Observe the skin’s reaction during application, particularly for signs of excessive redness or discomfort.
• Adhere to timing guidelines: Follow the recommended duration for leaving the peel on the skin, as specified in the product instructions.

After procedure

• Neutralise if required: If the protocol specifies, apply a neutralising solution to halt the peeling process.
• Soothe the skin: Use a post-treatment serum or soothing cream to reduce redness and enhance comfort.
• Provide aftercare instructions: Advise the patient to use SPF 50+ daily and avoid harsh products for at least a week.
• Schedule follow-up: Recommend a timeline for follow-up treatments or additional sessions if necessary.

Guidelines for Proper Aftercare

Proper post-care ensures the best results and minimizes potential side effects, so ensure your patients respect the following:

• Moisturise regularly: Use a gentle, hydrating product to combat dryness.
• Avoid active ingredients: Refrain from using other exfoliants or retinoids for at least a week.
• Skip physical exfoliation: Avoid scrubbing the skin to prevent irritation.
• Apply sunscreen: Use SPF 50+ daily to protect against UV rays.
• Limit heat exposure: Avoid saunas and hot showers until the skin recovers.

Duration of Azelac RU 60ml Effects

Results from Azelac RU treatments are typically long-lasting. To maintain optimal brightness and evenness, follow-up treatments every 4-6 months are recommended.

Potential Risks and Side Effects

While Azelac RU 60ml is generally well-tolerated, some patients may experience side effects. These can vary in severity depending on individual skin sensitivity and adherence to aftercare protocols. 

Common side effects:

• Redness and irritation: Temporary erythema is common immediately after the procedure.
• Dryness: Treated areas may feel tight or dehydrated for a few days post-treatment.
• Mild peeling: Light flaking as dead skin cells shed is a natural part of the healing process.
• Stinging sensation: A mild burning or stinging sensation during application, which typically subsides shortly after.
• Itching: The skin may feel itchy as it heals, particularly in sensitive areas.

Less common side effects:

• Increased sensitivity to sunlight: Heightened vulnerability to UV exposure, requiring strict sun protection.
• Post-inflammatory hyperpigmentation (PIH): Temporary darkening of treated areas, more common in darker skin tones.
• Blistering or crusting: In rare cases, small blisters or scabs may develop, especially if the peel is too strong for the skin type.
• Persistent redness: Prolonged erythema in sensitive individuals, which may require medical attention.
• Swelling: Mild puffiness in the treated area, typically resolving within 24 hours.

Rare side effects:

• Scarring: Extremely rare but possible, especially in individuals prone to keloid formation.
• Allergic reactions: Symptoms such as hives, swelling, or severe itching due to sensitivity to the peel’s ingredients.
• Erythema Multiforme: A rare inflammatory reaction presenting red or purple patches on the skin.
• Infection: Improper aftercare or application on compromised skin can lead to bacterial or fungal infections.
• Skin discolouration: Hypopigmentation (loss of skin colour) or hyperpigmentation (dark patches) that may require additional treatment.
• Delayed healing: Prolonged recovery time, particularly in patients with underlying health conditions or poor aftercare compliance.

Azelac RU 60ml Treatment Contraindications

Azelac RU 60ml is not suitable for all patients. A detailed assessment should be conducted to identify any of the following contraindications:

• Use of isotretinoin: Patients should avoid treatment if they’ve used isotretinoin or similar retinoids in the past six months.
• Pregnancy and breastfeeding: Active acids in the formula may not be safe for use during these stages.
• Keloid scarring history: Individuals prone to keloid formation are at higher risk of adverse skin reactions.
• Photosensitivity disorders: Conditions such as lupus erythematosus make patients more sensitive to UV exposure.
• Active skin infections: Avoid treatment in areas affected by bacterial, viral, or fungal infections like herpes simplex.
• Open wounds or cuts: Treating compromised skin increases the risk of irritation or infection.
• Severe acne or inflammation: Patients with active, inflamed acne should address the condition before chemical peel treatments.
• Recent laser or exfoliation treatments: Allow the skin to heal fully after procedures such as laser therapy or microdermabrasion.
• Sunburned or tanned skin: UV-damaged skin is more prone to adverse reactions.
• Eczema, psoriasis, or rosacea: These inflammatory skin conditions may worsen after treatment.
• Immunosuppressed patients: Reduced healing capacity increases the risk of complications.
• Patients on blood thinners: There is an increased risk of bleeding or delayed recovery.
• Allergy to peel ingredients: Hypersensitivity to azelaic acid, mandelic acid, or other components makes the product unsuitable.